Pipeline

AQ4N: our lead clinical programme

AQ4N is OncoTherics’ lead clinical-stage asset, with an initial focus on glioblastoma. It is a unidirectional hypoxia-activated prodrug designed to target cancer cells in low-oxygen regions of tumours.

Its development is supported by previous clinical experience and published evidence of activation in human tumour tissue.

OCT1002: the next generation

OCT1002 is our separately patented, second-generation unidirectional hypoxia-activated prodrug in advanced preclinical development.

Its initial focus is prostate cancer, with potential applications in other hypoxic solid tumours. Published preclinical research supports its potential to target treatment-resistant cancer cells.

ASSET INITIAL FOCUS PRECLINICAL PHASE I PHASE II PHASE III
AQ4N
Clinical lead
Newly diagnosed
glioblastoma (GBM)
Completed Completed Planned —
OCT1002
Second generation
Prostate cancer
Potential expansion into other hypoxic solid tumours
Advanced — — —